| # | Mannschaft | P |
|---|---|---|
| 1 | Bayern Munich | 13 |
| 2 | Wolfsburg | 13 |
| 3 | Borussia Dortmund | 12 |
| 4 | Bayer 04 Leverkusen | 10 |
| 5 | Mainz | 10 |
| 6 | SC Freiburg | 9 |
| 7 | FC Cologne | 8 |
| 8 | Union Berlin | 6 |
| 9 | Hertha Berlin | 6 |
| 10 | TSG 1899 Hoffenheim | 5 |
| 11 | Augsburg 1907 | 5 |
| 12 | RB Leipzig | 4 |
| 13 | Arminia Bielefeld | 4 |
| 14 | Stuttgart | 4 |
| 15 | Eintracht Frankfurt | 4 |
| 16 | Borussia Mönchengladbach | 4 |
| 17 | VFL Bochum | 3 |
| 18 | Greuther Fürth | 1 |
| 24/09/2021 | ||
| Greuther Fürth | 19:30 | Bayern Munich |
| 25/09/2021 | ||
| Union Berlin | 14:30 | Arminia Bielefeld |
| TSG 1899 Hoffenheim | 14:30 | Wolfsburg |
| RB Leipzig | 14:30 | Hertha Berlin |
| Bayer 04 Leverkusen | 14:30 | Mainz |
| Eintracht Frankfurt | 14:30 | FC Cologne |
| Borussia Mönchengladbach | 17:30 | Borussia Dortmund |
| 26/09/2021 | ||
| VFL Bochum | 14:30 | Stuttgart |
| SC Freiburg | 16:30 | Augsburg 1907 |